Human osteoblasts within soft peptide hydrogels promote mineralisation in vitro
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چکیده
منابع مشابه
Human osteoblasts within soft peptide hydrogels promote mineralisation in vitro
Biomaterials that provide three-dimensional support networks for the culture of cells are being developed for a wide range of tissue engineering applications including the regeneration of bone. This study explores the potential of the versatile ionic-complementary peptide, FEFEFKFK, for such a purpose as this peptide spontaneously self-assembles into β-sheet-rich fibres that subsequently self-a...
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Due to the weak regeneration potential of cartilage, there is a high clinical incidence of articular joint disease, leading to a strong demand for cartilaginous tissue surrogates. The aim of this study was to evaluate a gelatin-based hydrogel for its suitability to support chondrogenic differentiation of human mesenchymal stem cells. Gelatin-based hydrogels are biodegradable, show high biocompa...
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osteomyelitis (bone tissue infection), is a very serious disease affecting many patients by destroying large portions of bone tissue. tigecycline is a recently available antibiotic to overcome bacteria resistance phenomena in bone tissue infections. no information is available regarding its direct effects on bone cells. We have demonstrated deleterious effects of high tigecycline concentrations...
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Background Rotavirus is the most prevalent cause of severe gastroenteritis, hospitalizations, and deaths among infants and young children, globally. No specific antiviral drug is available against rotavirus infection. Objective The current study aimed to assess the antiviral effect of human cathelicidin antimicrobial peptide LL-37 on rotavirus infection in vitro. Methods This study was con...
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Hydrogels have been used primarily in the pharmaceutical field as carriers for delivery of various drugs, peptides and proteins. These systems have included stimuli-responsive gels that exhibit reversible swelling behavior and hence can show modulated release in response to external stimuli such as pH, temperature, ionic strength, electric field, or specific analyte concentration gradients. The...
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ژورنال
عنوان ژورنال: Journal of Tissue Engineering
سال: 2014
ISSN: 2041-7314,2041-7314
DOI: 10.1177/2041731414539344